As all roads lead to Rome, all roads lead out of Rome as well. Spin the dial, any direction will do.
East? Marche, Abruzzo.
South? Campania, Basilicata, Calabria.
North? Umbria, Romagna.
West? Sardegna, Maremma.
Does it really matter? If you are a trophy hunter, it does. You’d have to go to Tuscany or Piedmont. Maybe the Veneto. Find a stash of Barolo or Brunello, dig in the cellars, among so many Bentleys, parked, waiting to be driven around the table.